Methylprednisolone in the eye

Dry-eye disease is well-recognized as a complex, chronic disease that needs chronic therapy. Methylprednisolone, sold under the brand names Depo-Medrol and Solu-Medrol among others, is a corticosteroid medication used to suppress the immune system and decrease inflammation. Other names: 6-Methylprednisolone, Methylprednisolone Acetate, Methylprednisolone Sodium Succinate uses generic names in all descriptions of drugs.

Methylprednisolone in the eye

Methylprednisolone in the eye

PRESCRIPTION: Yes GENERIC AVAILABLE: Yes USES: Methylprednisolone is used to achieve prompt suppression of inflammation. The main treatment options for traumatic optic neuropathy (TON) include systemic corticosteroids and surgical optic nerve decompression, either alone or in combination.

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  • The major problems associated with the use of corticosteroids for the treatment of ocular diseases are their poor intraocular penetration to the posterior segment when administered loy and their secondary side effects when given systemiy.


    Methylprednisolone in the eye

    Methylprednisolone in the eye

    Methylprednisolone in the eye

    Usually given as tapering dose once or twice daily for several months Indications: Optic neuropathy (V), Inflammatory soft tissue changes (I), progressive strabismus (S) Effectiveness: Retrospective studies show 60% short-term benefit in reducing inflammatory sns; no proof of ultimate reduction in strabismus (diplopia) or ocular restriction Side-effects: Cushing’s disease (moon-face, weht gain, acne, adrenal insufficiency), diabetes, insomnia, mood disturbances, osteopenia, necrosis of femoral head, susceptibility to infections Dose: 1 gm methylprednisolone alternate days for 3 sessions; repeat cycle every 3 – 6 weeks PRN 500 mg MP weekly for 4 weeks, then 250 mg weekly for 16 weeks: maximal dose 8.0 gms Indications: Same as oral prednisone Effectiveness: 85% effective in reducing inflammatory sns Side-effects: Fewer than oral prednisone; however, electrolyte disturbances and cardiac arrhythmias have been reported monitoring is important; liver toxicity and death have been reported in cumulative dosing over 9 gms MP. Methylprednisolone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands.

    Methylprednisolone in the eye

    Review and analysis of the literature are complicated by the variety of therapeutic approaches and a lack of randomized, controlled studies on the use of these modalities for TON. PREDNISONE AND CHEST BURNING


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