Atorvastatin Side Effects, Dosage, Uses & More - Healtine Indicated as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls aged 10-17 years with He FH who have an inadequate response to diet alone (ie, LDL-C remains ≥190 mg/d L or LDL-C remains ≥160 mg/d L and there is positive family history or early CV disease or 2 or more other CVD risk factors present) Insomnia (1-5%) Urinary tract infection (4-8%) Nausea (4-7%) Dyspepsia (3-6%) Increased transaminases (2-3%) Muscle spasms (2-5%) Musculoskeletal pain (2-5%) Myalgia (3-8%) Limb pain (3-8%) Pharyngolaryngeal pain (1-4%) Nonserious and reversible cognitive side effects may occur Increased blood sugar and glycosylated hemoglobin (Hb A1c) levels reported with statin intake Use with caution in the elderly; risk of myopathy Heavy alcohol use, renal failure, history of liver disease Fatal and nonfatal hepatic failure reported (rare) Risk of rhabdomyolysis Risk of myopathy: Increased by coadministration with fibrates, niacin, cyclosporine, macrolides, telaprevir, boceprevir, combinations of HIV protease inhibitors (eg, saquinavir plus ritonavir, lopinavir plus ritonavir, tipranavir plus ritonavir, darunavir plus ritonavir, fosamprenavir, and fosamprenavir plus ritonavir), or azole antifungals Withhold or discontinue treatment in any patient developing myopathy, renal failure, or transaminase levels 3x ULN Temporary therapy discontinuation recommended for patients with acute surgical or medical conditions, elective major surgery, or serious condition suggestive of a myopathy or risk factor predisposing to development of renal failure secondary to rhabdomyolysis Rare reports of immune-mediated necrotizing myopathy (IMNM), characterized by increased serum creatine kinase that persists despite discontinuation of statin Use caution in hepatic impairment, recent stroke CYP3A4 substrate; avoid grapefruit products and caution with other CYP3A4 inhibitors Secondary causes of hyperlipidemia should be ruled out before initiating therapy SLCO1B1 (OATP1B1) CC genotype snificantly increases AUCs of parent drug and metabolites compared with the CT or TT genotypes This polymorphism is proposed to reduce transport into the liver, the main site of statin metabolism and elimination SLCO1B1 polymorphism is thought to have a lesser effect on the more hydrophilic statins (eg, rosuvastatin, fluvastatin) compared with those that are more lipophilic (eg, atorvastatin, simvastatin) Other genetic polymorphisms of elimination (eg, CYP450, P-glycoprotein) for each individual drug must also be considered, to explain variability for statin clearance among patients that exhibit SCLO1B1 polymorphism SLCO1B1 CC genotype is most common in Caucasians and Asians (15%) Risk of myopathy is 2.6- to 4.3-fold hher if the C allele is present and 16.9-fold hher in CC homozygotes than in TT homozygotes The above information is provided for general informational and educational purposes only. Atorvastatin is available as a brand-name drug ed Lipitor. It is also. These may include bile acid resins and other cholesterol-lowering medications.
Atorvastatin Oral Route Description and Brand Names - Mayo Clinic Statins, also known as HMG-Co A reductase inhibitors, are a class of lipid-lowering medications. Dec 1, 2015. US Brand Name. Lipitor. Atorvastatin is used together with a proper diet to lower cholesterol and. Other Topics in Patient Care & Health Info.
Types of Statins - Statin Answers – How much can a person save now that Lipitor is available generiy? Pitavasatin, rosuvastatin, atorvastatin, pravastatin, fluvastatin, and lovastatin. by the pharmaceutical company Pfizer and sold under the name Lipitor. 2011, at which time other companies were allowed to make and sell generic forms of this.
Lipitor atorvastatin dosing, indications, interactions, adverse effects. There are seven different statin drugs available for prescription in the US. Medscape - Hypercholesterolemia, hyperlipidemia-specific dosing for Lipitor atorvastatin, frequency-based adverse effects. Brand and Other NamesLipitor.
Crestor, Lipitor, and Other Cholesterol Drugs Statins Atorvastatin is a cholesterol-lowering which used used to treat hh cholesterol or to lower the risk of stroke, heart attack or other heart complications in patients with coronary heart disease or second type of diabetes. If you have suffered injuries or serious side-effects caused by a cholesterol drug ed "statins" you are taking, you may have a defective product liability claim.
Lipitor other name:
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